Frequently Asked Questions

Every question we've ever been asked.

faq

Nine years of patient questions, organised and answered in plain English. Search for what you need, browse by topic, or scroll through the lot. If your question isn’t here, we’d genuinely like to know — there’s a way to ask us at the bottom of the page.

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What people ask first.

The seven questions that come up on almost every discovery call. If you’re in a hurry, start here.

About the clinic.

Who we are, where we are, and how we’re set up.

Who is Save Minds?

Save Minds is a Centre for Precision Neuropsychiatry & Rapid-Acting Interventions — a private mental health clinic specialising in IV ketamine infusion therapy for treatment-resistant conditions, including depression, anxiety, PTSD, OCD, and suicidal ideation. For people who haven’t found relief through standard therapies, we offer care that is private, closely monitored, and led by a team of consultants. We are the UK’s first consultant-led clinic of our kind outside the NHS, based in St John’s Wood, London.

Our clinic is The Aura Centre, Charlbert Street, St John’s Wood, London NW8 7BT. The closest tube is St John’s Wood station on the Jubilee line.

Save Minds opened in 2017.

Yes. Save Minds is registered with the Care Quality Commission (CQC), the independent regulator of health and social care in England, and has been inspected and rated Good.

We are a private clinic. We do not accept NHS funding, NHS referrals on an NHS-funded basis, or NHS waiting-list placements. Treatment is self-funded. The only NHS ketamine clinic in the UK is at Oxford, which operates separately with limited capacity.

More than 500 patients to date, with over 5,000 ketamine treatments delivered. Approximately 30–40% of our patients travel from outside the UK — primarily from Europe and the Middle East.

Yes. Ketamine is a licensed prescription medication in the UK, used routinely as an anaesthetic and increasingly in mental health treatment. Use of ketamine for treatment-resistant mental health conditions is currently classified as “off-label” — meaning it’s used for a purpose outside its original licence — but this is both legal and clinically supported. NHS Oxford uses the same approach.

No. Save Minds is independently owned and operated, with one clinic delivering all treatment.

How ketamine actually works.

The science behind why ketamine is different — and what it isn’t.

What is ketamine therapy?

Ketamine therapy is a treatment for severe, treatment-resistant mental health conditions, using carefully controlled doses of ketamine delivered intravenously under continuous medical supervision. It works through a completely different brain pathway from traditional antidepressants — promoting neuroplasticity rather than topping up specific neurotransmitters.

Traditional antidepressants like SSRIs target serotonin, norepinephrine, and dopamine — neurotransmitters used by around 10% of the brain. Ketamine works on the glutamate system, which governs roughly 80% of the brain’s adaptability and learning. By promoting rapid neural growth (via a protein called BDNF), it helps restore the brain’s natural ability to form healthier patterns — which is why it works for patients who haven’t responded to standard treatments.

Oral, nasal, and intramuscular ketamine all have unpredictable absorption — two patients on the same dose can end up with very different drug levels in the bloodstream. IV infusion gives precise, controlled dosing in real time, with the ability to adjust mid-session. Every major published clinical trial demonstrating ketamine’s effect on depression has used IV delivery.

No. Ketamine has been used as an anaesthetic in operating theatres since the 1960s. Its use for treatment-resistant depression has been studied since the year 2000, with growing clinical and research support. In 2019, esketamine (a closely related form) was approved by the FDA as a Breakthrough Therapy for treatment-resistant depression — the first new mechanism approved for depression in over fifty years. We’ve been delivering it in private practice for over eight years.

No. Some clinics combine ketamine with structured psychotherapy sessions during the infusion. We take a different approach — focused on the neuroplastic effect of the medication itself, with the recovery work done through regular monitoring and patient self-direction. Many of our patients see their own therapists separately during and after treatment, but we do not offer therapy in-house.

Pharmacologically, yes — ketamine is the exact same drug molecule. However, the purity, context, dose, and supervision are completely different. Purity: medical ketamine is pharmaceutical-grade, 100% pure, and free from contaminants — recreational street ketamine is unregulated and frequently mixed with harmful fillers, bacteria, or dangerous adulterants like fentanyl. Context: therapeutic ketamine is administered in a safe, controlled clinical environment, while recreational use occurs entirely outside of a medical setting. Dose: medical treatments use precise, low doses well below anaesthetic levels, whereas recreational use involves unpredictable, often much higher doses. Supervision: patients receive continuous medical monitoring by trained professionals, while recreational use is self-administered without any safety oversight, making it genuinely harmful.

There is no published evidence of addiction from medically supervised ketamine therapy. Patients leave the clinic without cravings — the treatment doesn’t produce a “high” worth chasing, and the dosing schedule (sessions weeks apart, gradually tapering) is designed specifically to avoid dependency. Recreational ketamine misuse is a separate, real concern — but it’s not what we deliver.

Spravato (esketamine) is a related compound delivered as a nasal spray, currently prescribed in some UK private clinics. It’s the only mental-health ketamine formulation specifically licensed for depression, and it’s the version covered by some private insurance. We use IV racemic ketamine, which has been studied much more extensively and (in our clinical view) delivers more reliable outcomes. Both work; we’ve chosen the IV route deliberately.

Who we can help — and who we can't.

Honest answers about whether we’re the right fit for your situation.

What conditions do you treat?

Treatment-resistant depression, refractory anxiety, post-traumatic stress disorder (PTSD), complex PTSD, obsessive-compulsive disorder (OCD), and severe suicidal ideation. We focus exclusively on these conditions.

A condition is generally considered treatment-resistant when you’ve tried at least two antidepressants at adequate doses, for adequate time, without sustained improvement — often alongside engagement with therapy that hasn’t been enough. If your situation broadly matches this, you’re likely a candidate.

The fastest way to find out is our short eligibility check, which takes under a minute. A consultant reviews every submission personally, and the Save Minds team responds within one working day.

No. You can book a discovery call and arrange a psychiatric consultation with us directly. A GP referral is not required.

We treat adults aged 18 and over. We don’t treat under-18s.

Patients with uncontrolled high blood pressure, unstable heart conditions, active psychotic disorders, untreated bipolar I disorder, current substance dependency, or who are currently pregnant. We also generally don’t treat patients who haven’t yet tried standard antidepressants and therapy — those routes should be explored through the NHS or your GP first.

Most of our patients do. Depression with anxiety, PTSD with depression, OCD with rumination — these combinations are common. Because ketamine works on the underlying neuroplasticity rather than on a single symptom, it tends to help several co-occurring conditions at once.

We currently don’t treat these as primary conditions. If you have bipolar depression that’s stable and you’re now stuck with treatment-resistant depressive symptoms specifically, that’s a different conversation — please reach out and we’ll be honest about whether we can help.

Please call 999 or Samaritans on 116 123 first. Crisis support is independent of Save Minds and must come first. Once you’re safe, we can absolutely help — and we have treated patients referred directly to us from NHS psychiatric inpatient units.

How a full programme is structured.

Frequency, duration, and what flexibility you have along the way.

How many sessions will I need?

A typical full programme is 15–20 sessions over 4–6 months. Around 50% of patients see significant change within the first 10 sessions. By session 20, around 75%+ have achieved a good response. Your consultant adjusts the exact number based on your individual response.

Most programmes run 4–6 months from your first session to your last. The first 6 weeks involve the highest session frequency (twice weekly); after that, sessions space out gradually as you improve.

The standard pattern is: twice weekly for the first 3–6 weeks (induction phase), then weekly, then fortnightly, then every 3–4 weeks. Around 20–30% of patients then move to optional maintenance treatments at 6–12 week intervals.

Yes. There is no commitment, no upfront package, and no cancellation fee. You pay per session as you attend. About 5% of patients discontinue treatment for various reasons — that’s always your call.

Generally not a problem. The flexibility of an outpatient programme allows for rescheduling — life happens. We do recommend keeping induction-phase sessions as consistent as possible for the best outcomes, but missing the occasional session doesn’t derail the programme.

Around 30–35% of patients benefit from occasional maintenance sessions every 6–12 weeks once the main programme ends. This is optional, decided based on your individual response, and tapered down further over time. Most patients eventually transition to fully independent management.

In almost all cases, no. You typically continue your existing medications throughout treatment. Decisions about reducing or stopping any medication happen later, gradually, and only in collaboration with your prescribing doctor.

All treatment is delivered personally by Dr Yadhu. There isn’t a roster of consultants to switch between. If for any reason the consultant–patient relationship isn’t working, we’d discuss that openly — but we don’t have alternative consultants on rotation.

What a treatment day actually looks like.

Before, during, and after — what to expect and how to prepare.

What happens at my first appointment?

Your first session is approximately four hours in total. It begins with a detailed introduction — including a PowerPoint presentation that walks you through the treatment clearly and gives you the opportunity to ask any questions. Blood tests and an ECG are then conducted before your first IV ketamine infusion takes place. The session is unhurried and designed to ensure you feel fully informed and comfortable before treatment begins. Plan to spend around four hours at the clinic for your first visit.

Yes — light fasting. Clear fluids are allowed up to 2 hours before; food up to 4 hours prior. This is a precaution against nausea, not a strict requirement.

In most cases, yes — continue your normal medications unless your consultant has specifically told you otherwise. Don’t change anything without checking with us first.

Most patients describe a peaceful, slightly dreamlike state — sometimes a floating or dissociative sensation. Some sessions feel emotionally significant; others feel like resting quietly. A brief cold sensation at the infusion site is normal. You remain conscious throughout, able to speak with your consultant, and able to ask for the infusion to be slowed or paused at any moment.

The infusion itself lasts approximately 50 minutes. Including pre-session check-in and post-session recovery, usual sessions are around two hours in total.

Yes. For your first session, we recommend music via the room’s speaker so we can communicate easily. From later sessions, you’re welcome to bring your own earphones, playlist, and eye mask. We provide all of these too — bring whatever feels familiar.

No. Your consultant is with you throughout the session, monitoring you continuously. You’re never left alone with the infusion running.

A trusted person can accompany you to and from the clinic — in fact, we recommend it so they can take you home afterwards. They are not permitted in the treatment room itself, but can wait in the reception area.

No. You cannot drive on the day of treatment. Most patients arrange a taxi, Uber, or a trusted person to drive them home. You can return to driving the day after the session.

Rest. Hydrate. Allow yourself a quiet evening. Most patients are ready to return to normal activities the next day, but some prefer to take the rest of the treatment day off work. Photography or filming during sessions is not permitted, for everyone’s privacy.

What we monitor for — and how.

The practical details on safety, side effects, and what happens if something feels wrong.

Is ketamine therapy safe?

Yes, when delivered by a properly trained consultant in a clinical setting. Ketamine has been used as an anaesthetic for over 50 years; the therapeutic dose used for mental health is well below anaesthetic levels. At Save Minds, all sessions are personally delivered by Dr Yadhu — a dual consultant in Anaesthesia and Intensive Care — with continuous monitoring of heart rate, blood pressure, and oxygen saturation throughout.

Most patients tolerate ketamine well. Possible side effects during the session include a feeling of dissociation, mild nausea, or a brief rise in heart rate or blood pressure. These typically resolve within an hour of the session ending. Less commonly, some patients experience headache or fatigue the day after a session.

You can communicate with your consultant throughout. If a session becomes uncomfortable — emotionally or physically — the infusion can be slowed, paused, or adjusted. Around 6 sessions in a typical 10-session course are reported as positive or therapeutic; some are more neutral; occasionally a session feels emotionally intense. We’re prepared for all of these.

Medically supervised ketamine therapy, at the doses and frequency we use, has no published evidence of long-term harm. Recreational ketamine misuse — daily or near-daily high-dose self-administration — is a separate concern that can lead to bladder and kidney damage; this isn’t a risk with the structured therapeutic protocol we follow.

Yes, continuously. Heart rate, oxygen saturation, and blood pressure are measured throughout every session using hospital-grade equipment. Your consultant remains present at all times.

Mild rises in heart rate and blood pressure are normal and expected during a ketamine infusion — and are part of why continuous monitoring matters. If readings cross specific clinical thresholds, your consultant has protocols in place to slow or pause the infusion. This is part of why ketamine therapy must be delivered by someone with anaesthesia and intensive-care training.

Yes — some medications can interact with ketamine. Your full medication list will be reviewed at your psychiatric consultation, and adjusted only if necessary, only in collaboration with your prescribing doctor. In almost all cases, no changes are needed.

How we measure what's changing.

How daily check-ins and clinical scales work, and what your data tells us.

How do you measure if treatment is working?

Through three layers of data: a daily two-question mood and anxiety check-in via text message; six core clinical scales reviewed throughout the programme (PHQ-9, GAD-7, QIDS-SR, RRS-10, C-SSRS, WEMWBS); and two condition-specific scales where applicable (Y-BOCS for OCD, NSESSS for PTSD). Your consultant reviews this live in a clinical dashboard.

Our proprietary in-house app sends you a short daily text-message check-in for mood and anxiety from day one. It takes under 30 seconds, captures your scores, and feeds into the clinical dashboard your consultant uses. Developed with Ditto Medical — a UK-based clinical technology partner.

Nothing happens. No penalty, no streak you’ll lose. Patterns matter more than perfection. If you forget for a few days, your overall trend is unaffected.

Yes. Every patient has access to their own scores and progress charts through our app — every daily score, every clinical scale, every trend. You see what your consultant sees.

Yes. Your data is stored on secure UK-hosted servers compliant with GDPR and NHS Digital standards. Only you and your treating consultant can access your personal records. Aggregated, fully anonymised data may be used internally to improve our programme — and occasionally for peer-reviewed publication — but always with consent and never in a way that identifies you

Yes. At any point during or after your programme, you can request a full export of every score, every chart, and every assessment we’ve recorded. Sent securely as a PDF report. No charge.

The honest answers on cost.

Fees, what’s covered, and what isn’t.

How much does treatment cost?

Discovery call: free. Psychiatric consultation: £450 (one-off, includes £100 admin fee). First treatment session: £990. Subsequent sessions: £595 each. Typical full programme: £10,000–£15,000 across 15–20 sessions.

No. Save Minds is a private clinic and the only NHS ketamine service is at Oxford, which operates separately. UK private medical insurers don’t currently cover ketamine for mental health because it’s classified as “off-label” use. We can provide receipts but cannot guarantee any reimbursement.

No. Fees are paid as you attend each session — never upfront, never in bulk. This protects your ability to stop treatment at any time without contractual pressure.

No discounted pricing structures, though we treat each enquiry on its own circumstances. If financial hardship is a significant factor, we’d rather hear about it upfront. Discovery calls remain free regardless.

Bank transfer for the £450 psychiatric consultation (paid in advance). Card payment (debit or credit, including American Express) on the day for treatment sessions. We don’t accept cheques or cryptocurrency.

No. You pay per session as you attend. No deposits or upfront packages.

You pay only for the sessions you’ve attended. Nothing further. No cancellation fee, no penalty. Your consultant will be honest about response — around 20–25% of patients don’t see strong response in the first 10 sessions, and fewer than 5% remain non-responsive at session 20. If you’re not responding, your consultant will discuss whether continuing makes sense.

Getting here, and getting started.

Location, transport, accommodation, and how quickly you can begin.

Where exactly is the clinic?

The Aura Centre, Charlbert Street, St John’s Wood, London NW8 7BT. We share the center with other premium medical services in St John’s Wood.

Closest tube: St John’s Wood (Jubilee line), about a 5-minute walk. Buses 13, 113, 187, and 274 stop nearby. Black cabs and ride-share services can pull up directly outside.

Limited paid street parking is available locally. We recommend public transport or ride-share where possible. If you do drive in, allow extra time to find a space.

Around 30–40% of our patients travel for treatment — from across the UK, Europe, and the Middle East. Many stay in nearby St John’s Wood or Marylebone hotels. We can suggest options for accommodation between sessions if you’re travelling longer distances.

Yes. We regularly treat patients who travel from the EU, Ireland, the Middle East, and occasionally further afield. International patients should expect to spend several weeks in London during the induction phase of treatment.

From completed eligibility check to first treatment is typically 1–2 weeks, depending on consultation scheduling and how quickly you’d like to move. Urgent cases can sometimes be accommodated within a few days.

What happens after the programme.

Ongoing support, maintenance treatments, and continuity of care.

What happens after my programme ends?

At the end of your active programme, your consultant will review your full clinical data with you, discuss whether maintenance sessions might be helpful, and provide a treatment summary to share with your GP (with your consent). Continued daily check-ins are optional and can continue indefinitely if you’d like.

Around 20–35% of patients benefit from occasional maintenance sessions every 6–12 weeks for a limited period (usually 6–18 months), tapering down over time. This is decided based on your individual response — not everyone needs maintenance.

Only with your written consent. We provide a structured clinical summary to your GP and any other treating clinicians at three points: programme start, mid-programme, and programme end. You receive a copy of everything sent. Nothing is shared without your explicit permission.

Your consultant remains available throughout — both during and after the programme. If symptoms recur, get in touch and we’ll discuss what makes sense. Sometimes that’s a few maintenance sessions; sometimes it’s a re-evaluation of the broader treatment picture; sometimes it’s a referral elsewhere.

Yes. Many of our maintenance patients have been with us for two or three years. As long as you remain clinically suitable, you can return for top-up sessions whenever genuinely needed — at the same per-session rate as during the main programme.

No formal community. We’ve chosen not to host patient groups because privacy and confidentiality are extremely important to many of our patients. If you’d like to talk to someone else who’s been through treatment, we can sometimes arrange a confidential conversation between consenting patients — please ask.

Something we haven't covered?

This page is the result of nine years of patient questions. If yours isn’t here, it’s a gap we’d rather close than ignore. Send us the question through any of the routes below — we’ll answer you personally, and if it’s a question others might ask, we’ll add it to this page (anonymously, of course).

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Whenever you’re ready, the first step is either a short eligibility check or a free discovery call with our team.