Anxiety Treatment
Clear the fog of anxiety. A different pathway for chronic, refractory anxiety.
For people whose anxiety hasn’t responded to SSRIs, SNRIs or CBT — the kind that doesn’t have a clear trigger and is just there, every day, in your chest, your stomach, your sleep. Our consultant-led IV ketamine programme in London works through a different mechanism. Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Home » Conditions » Anxiety
- The Science
How ketamine is thought to act in anxiety — a different proposed mechanism.
SSRIs and SNRIs act on serotonin. Ketamine is thought to act on the glutamate system. Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Calms the Hyperactive Amygdala
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Restores Prefrontal Control
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Rebuilds Synaptic Plasticity
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Resets the Stress Response
Effects on the stress response are under investigation
Outcomes are monitored using validated clinical measures.
- The Programme
What treatment actually looks like.
Every step is consultant-led. Every session is monitored. And between sessions, we track how you’re responding daily — not at your next appointment three months from now.
Consultant Assessment
A consultant psychiatrist reviews your medical history, anxiety presentation, and previous treatments. We screen for anything that would make treatment unsafe and take baseline measures on validated scales (GAD-7, HAM-A) so we can track your response objectively.
Preparation
You’ll fast for 4–6 hours before your session and arrange transport home. On arrival you’re settled in a private treatment room — dim lighting, quiet, comfortable — before your consultant confirms the plan with you.
IV Infusion
Ketamine is delivered intravenously over 40–60 minutes at a subanaesthetic dose (typically 0.5 mg/kg), titrated to your weight and response. Heart rate, blood pressure and oxygen saturation are monitored throughout by a consultant anaesthetist.
Recovery & Debrief
You’ll rest in the clinic for 30–60 minutes as the acute effects wear off. Most people are back to their baseline within a few hours. Before you leave, we debrief the session and confirm the plan for the days ahead.
The Programme & Follow-Up
A full course is typically 6–8 sessions across 3–4 weeks. Between sessions, daily WhatsApp check-ins and validated scales let your consultant adjust the plan in real time. Booster sessions are scheduled based on how long your response holds.
- Refractory
Refractory Anxiety.
Chronic, treatment-resistant anxiety that hasn’t responded to medication or therapy. The kind that doesn’t have a clear trigger — it’s just there, every day, in your chest, your stomach, your sleep, your decision-making.
Who this is for
- Generalised anxiety that's persisted despite SSRIs or SNRIs
- Panic disorder unresponsive to CBT
- Health anxiety, social anxiety, or constant rumination
- Physical symptoms — chest tightness, tremor, GI issues — with no medical cause
- Inability to sleep or relax even when nothing is wrong
How we help
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Consultant-led from day one
Your treatment is planned and delivered by a consultant psychiatrist and consultant anaesthetist — not delegated to junior clinicians.
Daily monitoring between sessions
Short WhatsApp check-ins plus validated clinical scales give your consultant real-time visibility of how you're responding — and let them adjust the plan session by session.
A programme designed to hold
The full course is 6–8 sessions across 3–4 weeks, with booster sessions timed to your individual response. Response varies between patients and long-term durability is uncertain.
Step out of the loop of chronic worry.
If anxiety medication and therapy haven’t given you lasting relief, the next step is a short eligibility check or a free, no-pressure call with our team.
IV ketamine is an unlicensed (off-label) prescription treatment for anxiety. It is not approved by the MHRA, FDA or NICE for this indication. Response varies between patients, side effects and risks are possible, and long-term outcomes remain uncertain. Treatment is delivered following individual medical and psychiatric assessment, and each treatment session is administered by a consultant.