OCD Treatment
Break the loop. A different pathway for treatment-resistant OCD.
For OCD that hasn’t responded to high-dose SSRIs — the condition that quietly consumes hours of the day, often invisible to everyone around you. Our consultant-led IV ketamine programme in London acts on a different neurotransmitter system. Proposed mechanisms are under investigation; evidence and expected response differ by condition.
- The Science
How ketamine is thought to act in OCD
SSRIs work on serotonin and often need very high doses in OCD — with limited success. Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Interrupts the Error-Checking Loop
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Quiets Intrusive Thoughts
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Rebuilds Neural Flexibility
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Works Where SSRIs Don't
OCD is often treated with high-dose SSRIs. Ketamine acts on a different neurotransmitter system. Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Outcomes are monitored using validated clinical measures.
- The Programme
What treatment actually looks like.
Every step is consultant-led. Every session is monitored. And between sessions we track Y-BOCS daily — not at your next appointment three months from now.
Consultant Assessment
A consultant psychiatrist reviews your OCD presentation, previous treatment (including SSRI dosing and ERP therapy), and comorbidities. We take baseline Y-BOCS scores so we can track your response objectively — the same scale used in every major OCD trial.
Preparation
You’ll fast for 4–6 hours before your session and arrange transport home. On arrival you’re settled in a private, quiet treatment room before your consultant confirms the plan with you.
IV Infusion
Ketamine is delivered intravenously over 40–60 minutes at a subanaesthetic dose, titrated to your weight and response. Heart rate, blood pressure and oxygen saturation are monitored throughout by a consultant anaesthetist.
Recovery & Debrief
You’ll rest for 30–60 minutes as the acute effects wear off. We debrief your experience of the session before you leave. Anxiety, dissociation, perceptual changes or other adverse experiences can occur; these are assessed and managed clinically.
The Programme & Follow-Up
A full course is typically 6–10 sessions across 3–5 weeks. Between sessions, daily WhatsApp check-ins and Y-BOCS tracking let your consultant see how you’re responding in real time and adjust the plan. Booster sessions are scheduled based on how long your response holds.
- Obsessive-Compulsive
Treatment-Resistant OCD.
For OCD that hasn’t responded to high-dose SSRIs. The condition that quietly consumes hours of a person’s day — often invisible to everyone around them.
Who this is for
- Diagnosed OCD with significant daily impact
- Tried SSRIs at the high doses OCD typically requires, without response
- Intrusive thoughts that dominate your mental life
- Compulsions consuming hours per day
- Pure-O presentations — mental compulsions, rumination, scrupulosity
How we help
Proposed mechanisms are under investigation; evidence and expected response differ by condition.
Consultant-led from day one
Your treatment is planned and delivered by a consultant psychiatrist and consultant anaesthetist — not delegated to junior clinicians.
Y-BOCS tracking between sessions
Short WhatsApp check-ins plus repeat Y-BOCS scoring give your consultant real-time visibility of how you're responding — and let them adjust the plan session by session.
A programme designed to hold
The full course is typically 6–10 sessions across 3–5 weeks, with booster sessions timed to your individual response. Response varies between patients and long-term durability is uncertain.
Get your hours back.
If high-dose SSRIs and ERP haven’t given you meaningful relief, the next step is a short eligibility check or a free, no-pressure call with our team.
IV ketamine is an unlicensed (off-label) prescription treatment for OCD. It is not approved by the MHRA, FDA or NICE for this indication. Response varies between patients, side effects and risks are possible, and long-term outcomes remain uncertain. Treatment is delivered following individual medical and psychiatric assessment, and each treatment session is administered by a consultant.